Fatty crystals in sclerema neonatorum.

Sclerema Neonatorum and its Relation to Fat Necrosis.

Sclerema neonatorum is a rare disease of earlv infancy, characterized by swellings in the subcutaneous fat, of characteristic distribultion on the back, shoulders, buttocks, and cheeks. In these lesions the fat crystallizes out during life, probably as reutral fat, and in well-marked cases the crystals give rise to an inflammatory reaction of the " foreign body " type, with giant cells. In thes...

Report of a Case of Sclerema Neonatorum

Sclerema Neonatorum Treated Successfully with Parenteral Steroids: An Experience from a Resource Poor Country

Sclerema neonatorum is a form of panniculitides characterized by diffuse hardening of subcutaneous tissue with minimal inflammation. It usually affects ill and preterm neonates. Prognosis is usually poor in many cases despite aggressive management. Various treatment modalities (antibiotics, intravenous immunoglobulin, steroids, and exchange transfusion) have been explained in literature. Steroi...

Radial nerve palsy associated with localized subcutaneous fat necrosis in the newborn.

Many writers use the terms ' sclerema neonatorum ' and ' adiponecrosis subcutanea neonatorum' in a synonymous sense, and this has caused some confusion, although the real and clinically useful distinction drawn by Gray (1926) between the generalized and serious variety of subcutaneous fat necrosis, and the localized and benign type has become widely accepted. In this paper two cases of the loca...

Sclerema Neonatorum in a Full-Term Infant Showing Favorable Prognosis

Sclerema neonatorum (SN) is a rare disease characterized by firm, indurated, waxy skin lesions extending throughout the body, sparing the fat-free soles, palms, and genitalia. The prognosis of SN is generally very poor, with a high fatality rate. We report the case of a full-term infant with delayed onset of SN showing good prognosis. A 4-month-old Korean male infant presented with diffuse waxy...